By Rudy Kouhoupt
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E. 29) is indicating there is no perturbation of the endogenous steady state. In most cases, the tracer perturbation is confined within a few percent; this range is usually small and the above conditions are likely to be satisfied. e. no assumptions about the system structure are required. Briefly, the test that M equals a constant is based on the following. If the tracee constant steady-state has been perturbed, then M becomes a function of time M(t). The measured concentration of the substance of interest in the accessible pool, is thus where V is the volume.
Two of the isotopes are stable, is an unstable emitter. and while the third, Carbon (symbol C), on the other hand, is characterized by 6 protons. Since the number of neutrons for carbon can range from 4 to 10, seven carbon isotopes exist in nature. Only two, and having 6 and 7 neutrons respectively are stable. Among the unstable isotopes, and are often employed in tracer studies in biology and medicine. The isotope is a isotope and is often used to create a radioactive tracer while a isotope, is used in positron emission tomography (PET) studies.
One sees in this example immediately a problem: some tracee can enter and leave the system from the non-accessible pool without even passing through the accessible pool. How can this affect parameter definitions and attempts to quantitate them? 3. The accessible pool is available for measurement. e. transport among system components and biochemical transformations, are “lumped” into the tracee recirculation/exchange arrow. The important point to note in this figure is that the input and output are no longer called de novo production and disposal, but tracee rate of appearance into and disappearance from the accessible pool.