Advances in Genetics by M. Demerec (Eds.)

By M. Demerec (Eds.)

This quantity in a sequence on genetics, emphasizes the range of genetic reviews. Articles hide the filamentous fungus neurospora, biogenesis of yeast ribosomes, evolutionary genetics of fish, drosophila transposable components and the dropophila gene zeste.

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Division, with thread uniting the two principal nuclear masses, seen in Fig. 78 (seventh nuclear element from left). 75. Wminute culture from a 18-hour culture, on bean agar. In the top chain of cells three division figures (at right) in dumbbell form; in the bottom chain, nuclear granules separated by lipid globules. 78. Same as 74 and 76. Short axial nuclear thread at right; nuclear substance in granules or transverse rods, with adjacent lipid globules. The large black globules are prespores.

These investigations were of special interest since they demonstrated for the first time in Neurospora the accumulation of a metabolic intermediate as a result of genetic blocking. It was found that a mutant strain which lacks the ability to convert anthranilic acid to indole and tryptophane (see Fig. 3) excretes anthranilic acid in amounts sufficient to be isolated from the medium. I n spite of the fact that sufficient tryptophane for growth of the mutant is supplied in the medium, the intermediate continues t o be produced in an automatic reaction and accumulates in the culture because of the absence of an effective mechanism for removing it.

Some have partial swellings, which contain a nuclear thread (Fig. 951, or closely related nuclear granuleR (Fig. 961, or a loose net of niaclcur threads (Fig. 97). 32 BERTHE DELAPOBTM PLATE V Magnification: 1600 X. W3-101. Spirillum praeclarum Collin from intestinal tract of tadpoles. Smeara fixed with Perenyi, then stained with iron hematoxylin and erythrosin. 98. Resting cell with nuclear substance (n) and cytoplaam (c) equally distributed. 99, 100. Accumulation of nuclear substance (n) and cytoplasm (c) in the region where the spore will be formed.

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